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A super-element approach for structural identification in time domain
LI Jie, ZHAO Xin
《机械工程前沿(英文)》 2006年 第1卷 第2期 页码 215-221 doi: 10.1007/s11465-006-0004-4
关键词: numerical effective decomposing parameterization procedure divide-and-conquer ability time-domain identification
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《医学前沿(英文)》 2012年 第6卷 第3期 页码 288-295 doi: 10.1007/s11684-012-0208-4
Tramadol is a potent analgesic. However, the analgesia efficacy of tramadol, particularly its minimum effective dose (MED), is not clear. The aim of this study is to find MED of tramadol for postoperative analgesia in infants. The continual reassessment method (CRM) was performed to find MED. Infants undergoing surgeries were included in the 3 phases of this series. In each phase, 24 participants were allocated a different tramadol dose. Pain intensity was measured by face, legs, activity, cry, consolability (FLACC) measurement at 3-hour intervals. Tramadol was considered ineffective if the FLACC score was higher than 4 in 10 at anytime. In phase 1, seven dose levels were used within the range 0.1–0.4 mg?kg-1·h-1. Phase 1 was insufficient to identify the MED, and we increased the dose to 0.4–0.8 mg?kg-1·h-1 in phase 2. Phase 2 was insufficient to identify the MED. In phase 3, local anesthetic wound infiltration was introduced, and the tramadol dose levels tested were the same as in phase 1. The successful analgesia probability of tramadol 0.4 mg?kg-1?h-1 was 82.1% (95% CI, 0.742–0.925) in phase 1. In phase 2, it was 84.7% (95% CI, 0.789–0.991) with the dose 0.8 mg?kg-1?h-1. Phase 1 and phase 2 were insufficient to identify the MED. In phase 3, the successful analgesia probability for dose 0.35 mg?kg-1?h-1was 96.7% (95% CI, 0.853–0.997).We have demonstrated that tramadol provides insufficient analgesia for surgeries considered to cause moderate-to-severe postoperative pain in infants if used as the sole analgesic, and that local anesthetic wound infiltration enhances the efficacy of tramadol.
关键词: tramadol minimum effective dose postoperative analgesia infants continual reassessment method
Developing effective tumor vaccines: basis, challenges and perspectives
XU Qingwen, CHEN Weifeng
《医学前沿(英文)》 2007年 第1卷 第1期 页码 11-19 doi: 10.1007/s11684-007-0003-9
关键词: development conventional identification elucidation Successful immunotherapy
Z-scheme CdS/WO on a carbon cloth enabling effective hydrogen evolution
《能源前沿(英文)》 2021年 第15卷 第3期 页码 678-686 doi: 10.1007/s11708-021-0768-6
关键词: photocatalysis CdS/WO3 carbon cloth Z-scheme hydrogen evolution
Pijush Samui, Jagan J
《结构与土木工程前沿(英文)》 2013年 第7卷 第2期 页码 133-136 doi: 10.1007/s11709-013-0202-1
关键词: unsaturated soil effective stress parameter Gaussian process regression (GPR) artificial neural network (ANN) variance
OPPORTUNITIES AND APPROACHES FOR MANIPULATING SOIL-PLANT MICROBIOMES FOR EFFECTIVE CROP NITROGEN USE
《农业科学与工程前沿(英文)》 2022年 第9卷 第3期 页码 333-343 doi: 10.15302/J-FASE-2022450
● Matching nitrification inhibitors with soil properties and nitrifiers is vital to achieve a higher NUE.
关键词: nitrogen microbiome NUE rhizosphere phyllosphere soil food web
《环境科学与工程前沿(英文)》 2023年 第17卷 第6期 doi: 10.1007/s11783-023-1671-7
● Dolomite-doped biochar/bentonite was synthesized for phosphate removal.
关键词: Biochar-bentonite composite Dolomite doping Phosphate adsorption Polymeric matrix membrane Adsorption-filtration dual functions Low-concentration phosphate
高永超,钱恒,刘丽梅,王云争,王玎
《中国工程科学》 2009年 第11卷 第9期 页码 74-77
搜索空间的规模和复杂程度是决定问题求解难度的重要因素,而解空间的信息往往可以引导搜索找到最优解。在已知JSP空间结构的基础上,提出一种空间收缩与划分算法。算法利用搜索算法获得的较优解,结合组合优化问题解的backbone的概念,将搜索空间收缩并划分为一个或多个优解域,在优解域内再进行小规模问题的优化。该算法不必在求解前或求解过程中进行大量的统计分析工作,可以利用求解信息对解空间的地形进行估计,提高求解速度和解的质量。实验结果也证明了算法的有效性。
Multistage analysis method for detection of effective herb prescription from clinical data
null
《医学前沿(英文)》 2018年 第12卷 第2期 页码 206-217 doi: 10.1007/s11684-017-0525-8
Determining effective traditional Chinese medicine (TCM) treatments for specific disease conditions or particular patient groups is a difficult issue that necessitates investigation because of the complicated personalized manifestations in real-world patients and the individualized combination therapies prescribed in clinical settings. In this study, a multistage analysis method that integrates propensity case matching, complex network analysis, and herb set enrichment analysis was proposed to identify effective herb prescriptions for particular diseases (e.g., insomnia). First, propensity case matching was applied to match clinical cases. Then, core network extraction and herb set enrichment were combined to detect core effective herb prescriptions. Effectiveness-based mutual information was used to detect strong herb–symptom relationships. This method was applied on a TCM clinical data set with 955 patients collected from well-designed observational studies. Results revealed that groups of herb prescriptions with higher effectiveness rates (76.9% vs. 42.8% for matched samples; 94.2% vs. 84.9% for all samples) compared with the original prescriptions were found. Particular patient groups with symptom manifestations were also identified to help investigate the indications of the effective herb prescriptions.
关键词: effective prescription detection herb set enrichment analysis core network extraction insomnia personalized treatment
UV-LED/P25-based photocatalysis for effective degradation of isothiazolone biocide
《环境科学与工程前沿(英文)》 2021年 第15卷 第5期 doi: 10.1007/s11783-020-1379-x
• UV-LED with shorter wavelength was beneficial for photocatalytic degradation.
关键词: Degradation Photocatalytic LED CMIT P25
《化学科学与工程前沿(英文)》 2023年 第17卷 第10期 页码 1555-1567 doi: 10.1007/s11705-023-2338-4
关键词: adipic acid loose nanofiltration membrane dye/salt selective separation steric hindrance charge effect
《农业科学与工程前沿(英文)》 2022年 第9卷 第2期 页码 177-186 doi: 10.15302/J-FASE-2021421
A range of plant species produce root exudates that inhibit ammonia-oxidizing microorganisms. This biological nitrification inhibition (BNI) capacity can decrease N loss and increase N uptake from the rhizosphere. This study sought evidence for the existence and magnitude of BNI capacity in canola ( Brassica napus). Seedlings of three canola cultivars, Brachiaria humidicola(BNI positive) and wheat ( Triticum aestivum) were grown in a hydroponic system. Root exudates were collected and their inhibition of the ammonia oxidizing bacterium, Nitrosospira multiformis, was tested. Subsequent pot experiments were used to test the inhibition of native nitrifying communities in soil. Root exudates from canola significantly reduced nitrification rates of both N. multiformis cultures and native soil microbial communities. The level of nitrification inhibition across the three cultivars was similar to the well-studied high-BNI species B. humidicola. BNI capacity of canola may have implications for the N dynamics in farming systems and the N uptake efficiency of crops in rotational farming systems. By reducing nitrification rates canola crops may decrease N losses, increase plant N uptake and encourage microbial N immobilization and subsequently increase the pool of organic N that is available for mineralization during the following cereal crops.
Cytokine storm and translating IL-6 biology into effective treatments for COVID-19
《医学前沿(英文)》 doi: 10.1007/s11684-023-1044-4
关键词: SARS-CoV-2 COVID-19 cytokine storm interleukin-6 tocilizumab
Neil Stephen LOPEZ, Anthony S.F. CHIU, Jose Bienvenido Manuel BIONA
《能源前沿(英文)》 2018年 第12卷 第3期 页码 389-399 doi: 10.1007/s11708-018-0578-7
Global CO2 emissions increased by 57.9% from 1990 to 2014, of which 21% is known to be from the transportation sector. In line with policy development, driving forces to energy consumption and emissions may be determined using decomposition analysis techniques. However, the detail of information required to perform such studies for the transportation sector in developing countries can be challenging. An attempt was made in this study to formulate a decomposition analysis framework considering data availability and limitation in developing countries. Furthermore, a suggestion of adjusting transport activity data using average oil price was proposed. An illustrative case study in the Philippines revealed that the most significant driver was transport activity, followed by energy intensity, and then population growth, which was both similar and contrary to all previous studies performed in developed and rapidly urbanizing countries, which pointed out to transport activity as the primary contributing force. For the Philippines, transport activity was an inhibiting force, whereas energy intensity was the primary contributing factor. The difference could be explained by the differences in mode shares and quality of life between countries. Looking at private vehicle ownership data, it is observed that growth rates are higher in the rural, than in the urban centers. Deriving from the findings, developing a comprehensive public transport plan is recommend for future growth areas, expansion and modernization of public transport services in the city, and strategic deployment of transport policies.
关键词: transportation LMDI decomposition developing country emissions
标题 作者 时间 类型 操作
Estimation of the minimum effective dose of tramadol for postoperative analgesia in infants using the
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期刊论文
Developing effective tumor vaccines: basis, challenges and perspectives
XU Qingwen, CHEN Weifeng
期刊论文
Determination of effective stress parameter of unsaturated soils: A Gaussian process regression approach
Pijush Samui, Jagan J
期刊论文
OPPORTUNITIES AND APPROACHES FOR MANIPULATING SOIL-PLANT MICROBIOMES FOR EFFECTIVE CROP NITROGEN USE
期刊论文
Facile fabrication of dolomite-doped biochar/bentonite for effective removal of phosphate from complex
期刊论文
Multistage analysis method for detection of effective herb prescription from clinical data
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期刊论文
and properties of PES/SPSf loose nanofiltration membranes using SPES as a hydrophilic polymer for the effective
期刊论文
ROOT EXUDATES FROM CANOLA EXHIBIT BIOLOGICAL NITRIFICATION INHIBITION AND ARE EFFECTIVE IN INHIBITING
期刊论文